RAPID POISON SCREENING BY INNOVATIVE FT-IR METHODOLOGY

A little kid was rushed into the ICU at a reputed hospital with suspected poisoning. The child had lost consciousness and was frothing at the mouth. The team of doctors at the ICU immediately rushed the ingested poison for poison screening to Ramaiah Advanced Testing Laboratory.

Research scientists within our team then inferred based on the information provided and available literature reviews that the poisoning effect could be due to toxic compounds belonging to the class of organochlorines, organophosphates, pyrethrins or related category of  pest-control treatment compounds.

Qualitative screening was carried out by FTIR, being the method of choice, as it enables a comparison of a fingerprint spectrum of the sample with that of a standard contained in the US or Indian Pharmacopoeia database of synthetic drug compounds. The FTIR spectrum of the sample thus derived was compared and found to match that of Ivermectin, a compound frequently used for anti-lice treatment.

In less than an hour, due to the cutting edge technology available at the Poison Screening lab at RATL, and the advanced methods of our lab and scientists, we were able to precisely identify the poisonous component in the lice powder as Ivermectin. The doctors treating the little child were then able to immediately chart a course of antidote and treatment, to ensure his recovery.

FTIR SPECTRAL DATA OF THE INGESTED POISON SAMPLE
FTIR SPECTRAL DATA OF THE INGESTED POISON SAMPLE
FTIR SPECTRAL DATA OF IVERMECTIN
FTIR SPECTRAL DATA OF IVERMECTIN

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